Biotechnology and its Applications — Revision Notes
BITSAT · Biology
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Key concepts, formulas, and definitions from Biotechnology and its Applications for BITSAT Biology preparation.
Key Topics to Revise
10.1 Biotechnological Applications in Agriculture
- Three options for increasing food production: agrochemical-based, organic, and genetically engineered crop-based agriculture
- Plant tissue culture is the technique of maintaining plant cells, tissues, or organs on artificial sterilized nutrient medium under controlled conditions
- Explant: any part of plant taken out and grown in test tube under sterile conditions
10.2 Biotechnological Applications in Medicine
- Recombinant DNA technology enables mass production of safe, effective therapeutic drugs
- About 30 recombinant therapeutics approved worldwide, 12 marketed in India
- E. coli initially used as host, yeast becoming preferred choice
10.3 Transgenic Animals
- Transgenic animal contains foreign gene (transgene) introduced by transfection
- Produced for studying normal physiology, disease models, biological products, vaccine safety, chemical safety testing
- First transgenic animal: mouse with growth hormone gene (supermouse)
10.4 Ethical Issues, Biopatents, and Molecular Diagnosis
- GEAC (Genetic Engineering Approval Committee) regulates GM research and safety
- Bioethical concerns: species integrity, environmental risks, humanness concept, animal suffering
- Biopiracy: unauthorized exploitation of biological resources by multinational companies
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Formula Sheet
Biotechnology and its Applications — formula sheet
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